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  • Writer's pictureDr. Ashley Corey

The New Long Lasting Neurotoxin: Try The Daxxify Difference

Updated: May 14

Skincare enthusiasts, rejoice! A groundbreaking neurotoxin called Daxxify by Revance has arrived at Wellspring Skincare, the premier skincare destination in Roswell, Georgia. As a leading med spa, Wellspring is always at the forefront of innovative treatments, and Daxxify is no exception. This remarkable neurotoxin offers a unique solution for achieving smoother, more youthful skin. In this comprehensive guide, we'll dive into the science behind Daxxify, its benefits, and how it's revolutionizing the skincare industry.

Interested in trying Daxxify for yourself? To help you determine if you "Love It", we are offing an introductory "Try It" pricing for all first time Daxxify patients at Wellspring Skincare. So why not see if it works for you?

What is Daxxify (aka Daxi) and How Does It Work?

DAXXIFY™ (DaxibotulinumtoxinA-lanm) for injection is the first and only FDA approved long-lasting peptideformulated neuromodulator product for use in adults for the temporary improvement of moderate to severe frown lines (glabellar lines). [1-2,7-11] DAXXIFY™ has the ability to deliver year-long results for patients with potentially only two treatments per year and has been proven to be effective, and generally safe and well tolerated. [2-5] DAXXIFY™ is powered by a cell-penetrating peptide technology (Peptide Exchange Technology™), Revance's proprietary, synthetic, 35-amino-acid stabilizing excipient with a highly positive charge, and is free of human serum albumin or animal-based components. [1,2,11] Manufactured exclusively in the U.S., DAXXIFY™ is the first true innovation in neuromodulator product formulation in over 30 years.
Revance has evaluated this neuromodulator formulation in other Phase 2 clinical studies in aesthetics, including the full upper face, forehead lines and crow’s feet as well as in therapeutic indications, including cervical dystonia and upper limb spasticity. Learn more at

Daxxify is a next-generation neurotoxin developed by Revance Therapeutics, a renowned company in the field of aesthetic medicine. It is designed to temporarily reduce the appearance of moderate to severe facial wrinkles and lines, particularly those in the forehead and around the eyes. Daxxify works by blocking the nerve signals that cause facial muscles to contract, leading to a smoother, more relaxed appearance.

before and after of daxxify wellspring skincare
Daxxify progression.

What Sets Daxxify Apart from Other Neurotoxins?

Daxxify's unique formulation makes it stand out from other neurotoxins on the market. Its innovative peptide technology allows for a longer-lasting effect and a more natural-looking result. According to clinical trials, 50% of patients receiving Daxi showed efficacy 6 months later. Some patients lasted up to 9 months!

Clinical trial data of Daxxify treatment effect duration.
Clinical trial data of Daxxify treatment effect duration.

The Benefits of Daxxify at Wellspring Skincare

Wellspring has proudly introduced Daxxify to its extensive list of cutting-edge treatments. Patients who choose Daxxify can enjoy a range of benefits, including:

  • Longer-lasting results: Daxxify is designed to provide results that last up to six months, allowing for fewer treatments and maintenance visits.

  • Quicker onset: Patients may see visible improvements in their skin within 24 to 48 hours after treatment, making Daxxify a great option for those seeking fast results.

  • Minimal downtime: Daxxify treatments typically require little to no downtime, allowing patients to resume their daily activities shortly after their appointment.

  • Safe and effective: Daxxify is FDA-approved and backed by extensive clinical research, ensuring its safety and effectiveness for patients.

The U.S. approval of DAXXIFY™ was based on the data generated in the SAKURA Phase 3 clinical trial program (SAKURA 1,2,3), which included more than 2,700 patients and approximately 4,200 treatments. In the pivotal trials:
  • 74% of subjects achieved a > two-grade improvement in glabellar lines at week 4 per both investigator and patient assessment [1,4]

  • 88% achieved > two-grade improvement at week 4 per investigator assessmen[1]

  • 98% of subjects achieved none or mild wrinkle severity at week 4 per investigator assessment [4]

  • 6-month median duration [3,4]

  • Some patients maintained treatment results at 9 months[2-4]

  • Results seen as early as one day after treatment, typically seen within two days [14]

Why Choose Wellspring Med Spa for Your Daxxify Treatment?

When it comes to enhancing your skincare routine, trust the experts at Wellspring Med Spa in Roswell, Georgia. Here's why:

  • Experienced professionals: The skilled team at Wellspring Skincare has extensive experience in administering neurotoxin treatments, ensuring you receive the highest level of care.

  • Personalized approach: Wellspring Skincare believes in providing personalized treatment plans tailored to each patient's unique needs and goals.

  • State-of-the-art facility: Wellspring boasts a modern, comfortable facility equipped with the latest technology and equipment to provide the best possible patient experience.

  • Exceptional patient care: Wellspring Skincare is committed to providing exceptional patient care and fostering long-lasting relationships with their clients.

Daxxify by Revance is a game-changing neurotoxin that is quickly becoming a top choice for patients seeking to rejuvenate their skin. With its innovative formulation, longer-lasting effects, and quick onset, Daxxify is an excellent addition to any skincare regimen. Experience the transformative power of Daxxify at Wellspring Skincare.


  1. Data on File. DAXXIFY™ Package Insert. Newark, CA: Revance Therapeutics, Inc, 2022.

  2. Fabi SG, Cohen JL, et al. DaxibotulinumtoxinA for Injection for the treatment of glabellar lines: efficacy results from SAKURA 3, a large, open-label, phase 3 safety study. Dermatol Surg. 2020. doi:10.1097/DSS.0000000000002531

  3. Carruthers JD, Fagien S, et al. DaxibotulinumtoxinA for Injection for the treatment of glabellar lines: results from each of two multicenter, randomized, double-blind, placebo-controlled, phase 3 studies (SAKURA 1 and SAKURA 2). Plast Reconstr Surg. 2020;145(1):45-58.

  4. Bertucci V, Solish N, et al. DaxibotulinumtoxinA for Injection has a prolonged duration of response in the treatment of glabellar lines: pooled data from two multicenter, randomized, double-blind, placebocontrolled, phase 3 studies (SAKURA 1 and SAKURA 2). J Am Acad Dermatol. 2020;82(4):838-845.

  5. Green JB, Mariwalla K, Coleman K, et al. A large, open-label, phase 3 safety study of daxibotulinumtoxinA for injection in glabellar lines: a focus on safety from the SAKURA 3 study. Dermatol Surg. 2020. doi:10.1097/DSS.0000000000002463

  6. Data on File. Protocols 1620301-303. Post Hoc Analysis. Newark, CA: Revance Therapeutics, Inc, 2021.

  7. Xeomin. Prescribing Information. Merz Pharmaceuticals GmbH; 2020.

  8. Dysport. Prescribing Information. Ipsen Biopharmaceuticals, Ltd; 2020.

  9. Jeuveau. Prescribing Information. Evolus, Inc; 2020.

  10. Botox Cosmetic. Prescribing Information. Allergan, Inc; 2020.

  11. Waugh JM, Lee J, Dake MD, Browne D. Nonclinical and clinical experiences with CPP-based self-assembling peptide systems in topical drug development. Methods Mol Biol. 2011; 683:553-572.

  12. Data on File. Harris Poll. Newark, CA: Revance Therapeutics, Inc, 2018.

  13. Decision Resources Group Aesthetics Injectables Market Insights Report, 2022.

  14. Data on File. D220801001. Newark, CA: Revance Therapeutics, Inc, 2022.

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